Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | HTT | P42858 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986901 | 0.80 | RAF1 (0.47) | MAPTHTTGAAALDH1A1HPGD | |
| SCHEMBL31276346 | 0.79 | MAPT (0.71) | MAPTHTTGAAALDH1A1HPGD | |
| SCHEMBL2162785 | 0.79 | MAPT (0.71) | MAPTHTTGAAALDH1A1HPGD | |
| SCHEMBL2162778 | 0.79 | MAPT (0.71) | MAPTHTTGAAALDH1A1HPGD | |
| SCHEMBL14537314 | 0.79 | MAPT (0.71) | MAPTHTTGAAALDH1A1HPGD | |
| SCHEMBL2989104 | 0.78 | AKR1C3 (0.53) | RAB9AHSP90AA1POLBNPC1KMT2A | |
| SCHEMBL341880 | 0.78 | KMT2A (0.53) | ALDH1A1RAB9AHSP90AA1NPC1SMN1; SMN2 | |
| SCHEMBL8837785 | 0.77 | ALDH1A1 (0.64) | MAPTHTTGAAALDH1A1HPGD | |
| SCHEMBL8837784 | 0.77 | ALDH1A1 (0.64) | MAPTHTTGAAALDH1A1HPGD | |
| SCHEMBL5946453 | 0.77 | MAPT (0.77) | MAPTHTTGAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116240560-A | Method for electrochemically synthesizing furoquinone by utilizing microchannel reactor | 南京工业大学 | 2023-06-09 | — | — | CN | disclosed |
| EP-0862560-B1 | SUBSTITUTED 2-ANILINOPYRIMIDINES USEFUL AS PROTEIN KINASE INHIBITORS | CELLTECH THERAPEUTICS LTD (GB) | 2003-04-02 | — | — | EP | disclosed |
| US-6235746-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATIVE AGENT | CELLTECH THERAPEUTICS, LIMITED (GB) | 2001-05-22 | — | — | US | disclosed |
| US-5958935-A | Substituted 2-anilinopyrimidines useful as protein kinase inhibitors | CELLTECH THERAPEUTICS LIMITED (GB) | 1999-09-28 | — | — | US | disclosed |