Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 18/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520757 | 0.83 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPT | |
| SCHEMBL7688645 | 0.81 | ELANE (0.54) | ELANELMNAMAPTNPSR1 | |
| SCHEMBL3150572 | 0.81 | ELANE (0.57) | ELANELMNAMAPTNPSR1 | |
| SCHEMBL15867625 | 0.80 | ELANE (0.61) | ELANELMNAMAPTNPSR1 | |
| SCHEMBL11419918 | 0.79 | ELANE (0.59) | ELANELMNAMAPTNPSR1 | |
| SCHEMBL7815596 | 0.79 | IDO1 (0.55) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL20512118 | 0.78 | ELANE (0.54) | ELANELMNAMAPTNPSR1 | |
| SCHEMBL14639250 | 0.78 | ELANE (0.50) | ELANELMNAMAPTNPSR1 | |
| SCHEMBL16940033 | 0.78 | ELANE (0.57) | ELANELMNAMAPTNPSR1 | |
| SCHEMBL23393760 | 0.76 | ELANE (0.56) | ELANENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324997-A2 | DIOXOLANE ANALOGS FOR IMPROVED INTER-CELLULAR DELIVERY | Shire Biochem Inc. (CA) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030922-A2 | DIOXOLANE ANALOGS FOR IMPROVED INTER-CELLULAR DELIVERY | SHIRE BIOCHEM INC. (CA) | 2002-04-18 | — | — | WO | disclosed |