Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683064 | 0.85 | ELANE (0.56) | ELANEL3MBTL1CXCL8NPSR1 | |
| SCHEMBL3150572 | 0.83 | ELANE (0.57) | ELANENPSR1LMNAMAPT | |
| SCHEMBL15867625 | 0.83 | ELANE (0.61) | ELANEL3MBTL1NPSR1LMNAMAPT | |
| SCHEMBL11419918 | 0.81 | ELANE (0.59) | ELANENPSR1LMNAMAPT | |
| SCHEMBL7685111 | 0.81 | PTGS2 (0.49) | ELANEL3MBTL1CXCL8LMNAMAPT | |
| SCHEMBL31112746 | 0.81 | PTGS2 (0.49) | ELANEL3MBTL1CXCL8LMNAMAPT | |
| SCHEMBL6974420 | 0.81 | ELANE (0.51) | ELANENPSR1LMNAMAPT | |
| SCHEMBL20512118 | 0.81 | ELANE (0.54) | ELANENPSR1LMNAMAPT | |
| SCHEMBL16940033 | 0.80 | ELANE (0.57) | ELANENPSR1LMNAMAPT | |
| SCHEMBL23393760 | 0.79 | ELANE (0.56) | ELANENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380388-B1 | ACTIVITY AGAINST RETROVIRUSES SUCH AS HUMAN IMMUNODEFICIENCY VIRUS (HIV), HEPATITIS B VIRUS (HBV), AND HUMAN T-LYMPHOTROPIC VIRUS | BRANTFORD CHEMICALS INC. (CA) | 2002-04-30 | — | — | US | claimed |
| US-6380388-B1 | ACTIVITY AGAINST RETROVIRUSES SUCH AS HUMAN IMMUNODEFICIENCY VIRUS (HIV), HEPATITIS B VIRUS (HBV), AND HUMAN T-LYMPHOTROPIC VIRUS | BRANTFORD CHEMICALS INC. (CA) | 2002-04-30 | — | — | US | disclosed |