Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 3/20 | 0.34 |
| ▸ | ADH1C | P00326 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976009 | 0.98 | CYP1A2 (0.38) | CYP1A2ADH1AADH1CSIGMAR1 | |
| SCHEMBL6974283 | 0.92 | ADH1C (0.33) | ADH1AADH1C | |
| SCHEMBL6963743 | 0.88 | ADH1A (0.37) | CYP1A2ADH1AADH1CSIGMAR1 | |
| SCHEMBL6975483 | 0.88 | ADH1A (0.36) | ADH1AADH1C | |
| SCHEMBL6975732 | 0.86 | ADH1A (0.39) | CYP1A2ADH1AADH1CSIGMAR1 | |
| SCHEMBL6975147 | 0.80 | ADH1A (0.37) | CYP1A2ADH1AADH1CSIGMAR1 | |
| SCHEMBL6975102 | 0.79 | ADH1C (0.37) | ADH1AADH1C | |
| SCHEMBL6971230 | 0.79 | ADH1A (0.37) | ADH1AADH1C | |
| SCHEMBL6973231 | 0.79 | — | — | |
| SCHEMBL6974972 | 0.79 | ADH1A (0.39) | ADH1AADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |