Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086333 | 0.91 | CYP1A2 (0.39) | CYP1A2CYP2C19MEN1KMT2ACYP2C9 | |
| SCHEMBL7084632 | 0.90 | SMN1; SMN2 (0.36) | CYP1A2CYP2C19MEN1KMT2ACYP2C9 | |
| SCHEMBL8116257 | 0.89 | MEN1 (0.39) | CYP1A2CYP2C19MEN1KMT2ACYP2C9 | |
| SCHEMBL7087523 | 0.88 | TOP2A (0.44) | CYP1A2CYP2C19MEN1KMT2ACYP2C9 | |
| SCHEMBL6974491 | 0.87 | MEN1 (0.37) | CYP1A2CYP2C19MEN1KMT2ACYP2C9 | |
| SCHEMBL7081639 | 0.87 | ALOX12 (0.38) | CYP1A2CYP2C19MEN1KMT2ACYP2C9 | |
| SCHEMBL6966247 | 0.86 | CYP1A2 (0.49) | CYP1A2CYP2C19MEN1KMT2ACYP2C9 | |
| SCHEMBL6975053 | 0.85 | MEN1 (0.41) | CYP1A2CYP2C19MEN1KMT2ACYP2C9 | |
| SCHEMBL7083140 | 0.85 | CYP2C9 (0.39) | CYP1A2CYP2C19MEN1KMT2ACYP2C9 | |
| SCHEMBL6974554 | 0.84 | MEN1 (0.31) | CYP1A2CYP2C19MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |