Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.59 |
| ▸ | FNTB | P49356 | 10/20 | 0.59 |
| ▸ | HTR2C | P28335 | 5/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | PLAUR | Q03405 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979050 | 1.00 | FNTA (0.59) | FNTAFNTBHTR2CPGGT1BPLAUR | |
| SCHEMBL6974495 | 0.91 | FNTA (0.49) | FNTAFNTBHTR2CPGGT1B | |
| SCHEMBL7648912 | 0.91 | FNTA (0.49) | FNTAFNTBHTR2CPGGT1B | |
| SCHEMBL27497642 | 0.82 | FNTA (0.58) | FNTAFNTBHTR2CPGGT1BPLAUR | |
| SCHEMBL7084118 | 0.82 | FNTA (0.62) | FNTAFNTBHTR2CPGGT1BPLAUR | |
| SCHEMBL27500777 | 0.81 | FNTA (0.62) | FNTAFNTBHTR2CPGGT1BMEN1 | |
| SCHEMBL7503755 | 0.79 | FNTA (0.56) | FNTAFNTBHTR2CPGGT1B | |
| SCHEMBL7515567 | 0.78 | FNTA (0.58) | FNTAFNTBHTR2CPGGT1BMEN1 | |
| SCHEMBL6971222 | 0.77 | FNTA (0.59) | FNTAFNTBHTR2CPGGT1BPLAUR | |
| SCHEMBL7084119 | 0.77 | FNTA (0.44) | FNTAFNTBHTR2CPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472526-B1 | SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE OR PHARMACEUTICALLY ACCEPTABLE SALTS OR ISOMERS THEREOF, IN PHARMACEUTICAL COMPOSITION AND INTERMEDIATES | LG CHEMICAL LTD. (KR) | 2002-10-29 | — | — | US | disclosed |