SCHEMBL6974535

SCHEMBL6974535

NC(CCN1CCCCC1)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 9/20 0.55
HRH3 Q9Y5N1 1/20 0.52
SIGMAR1 Q99720 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
SLC6A3 Q01959 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5757757 0.88 ALDH1A1 (0.53) SIGMAR1MEN1KMT2ASLC6A3
SCHEMBL6009479 0.88 ALDH1A1 (0.53) SIGMAR1MEN1KMT2ASLC6A3
Hydrochloric Acid SCHEMBL5756120 0.86 ALDH1A1 (0.51) SIGMAR1MEN1KMT2ASLC6A3
SCHEMBL28316666 0.86 ALDH1A1 (0.54) LTA4HSIGMAR1MEN1KMT2ASLC6A3
SCHEMBL9796769 0.86 ALDH1A1 (0.54) LTA4HSIGMAR1MEN1KMT2ASLC6A3
Hydrochloric Acid SCHEMBL5757965 0.84 ALDH1A1 (0.53) SIGMAR1MEN1KMT2ASLC6A3
SCHEMBL6980055 0.82 GRIN2D (0.56) LTA4HHRH3SLC6A3
Oxalic Acid SCHEMBL27277928 0.81 KMT2A (0.52) MEN1KMT2A
SCHEMBL4731648 0.78 MEN1 (0.55) HRH3MEN1KMT2ASLC6A3
SCHEMBL10672928 0.78 HRH3 (0.50) HRH3SIGMAR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1294690-A2 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY Bristol-Myers Squibb Pharma Company (US) 2003-03-26 EP disclosed
EP-1158980-A4 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY DU PONT PHARM CO (US) 2002-04-03 EP disclosed
WO-2001098270-A2 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2001-12-27 WO disclosed
EP-1158980-A1 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY Du Pont Pharmaceuticals Company (US) 2001-12-05 EP disclosed
WO-2000035453-A1 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY DU PONT PHARMACEUTICALS COMPANY (US) 2000-06-22 WO disclosed