Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979685 | 0.83 | GAA (0.47) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL15349556 | 0.80 | DYRK1A (0.56) | DYRK1AMEN1KMT2ALMNAMAPT | |
| SCHEMBL1040735 | 0.78 | DYRK1A (0.63) | DYRK1AMEN1KMT2ALMNAMAPT | |
| SCHEMBL2762212 | 0.78 | MEN1 (0.61) | DYRK1AMEN1KMT2ALMNAMAPT | |
| SCHEMBL1043301 | 0.77 | DYRK1A (0.61) | DYRK1AMEN1KMT2ALMNAMAPT | |
| SCHEMBL15349917 | 0.77 | DYRK1A (0.65) | DYRK1AMEN1KMT2ALMNAMAPT | |
| SCHEMBL6979211 | 0.76 | RAB9A (0.58) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL1038566 | 0.76 | TDP1 (0.62) | DYRK1AMEN1KMT2ALMNAMAPT | |
| SCHEMBL6979367 | 0.74 | MAPT (0.57) | DYRK1AMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1041605 | 0.73 | DYRK1A (0.57) | DYRK1AMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006114-B1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | GRELAN PHARMACEUTICAL CO (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-6136831-A | ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL AGENTS, ENZYME INHIBITORS | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1006114-A1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | Grelan Pharmaceutical Co., Ltd. (JP) | 2000-06-07 | — | — | EP | disclosed |