Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 16/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981032 | 0.92 | OPRD1 (0.38) | OPRD1OPRK1OPRL1OPRM1 | |
| SCHEMBL6969796 | 0.88 | OPRD1 (0.42) | OPRD1OPRK1OPRL1OPRM1ALDH1A1 | |
| SCHEMBL6967337 | 0.86 | OPRD1 (0.39) | OPRD1OPRK1OPRL1OPRM1 | |
| SCHEMBL6979664 | 0.86 | OPRD1 (0.37) | OPRD1OPRK1OPRL1OPRM1 | |
| SCHEMBL6970452 | 0.86 | OPRD1 (0.40) | OPRD1OPRK1OPRL1ALDH1A1CYP2D6 | |
| SCHEMBL6974993 | 0.85 | CCR3 (0.41) | OPRD1OPRK1OPRL1OPRM1ALDH1A1 | |
| SCHEMBL6973626 | 0.85 | OPRD1 (0.40) | OPRD1OPRK1OPRL1OPRM1ALDH1A1 | |
| SCHEMBL6971228 | 0.84 | ADRA1A (0.44) | OPRD1OPRK1OPRL1OPRM1 | |
| SCHEMBL6980433 | 0.84 | OPRD1 (0.42) | OPRD1OPRK1OPRL1OPRM1ALDH1A1 | |
| SCHEMBL6969075 | 0.84 | OPRD1 (0.38) | OPRD1OPRK1OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202984-B1 | DIPHENYL-PIPERIDINE DERIVATE | ASTRAZENECA UK LTD (GB) | 2003-03-05 | — | — | EP | claimed |