Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 7/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128102 | 1.00 | DHFR (0.53) | DHFR | |
| SCHEMBL9916086 | 0.94 | DHFR (0.54) | DHFR | |
| SCHEMBL9916149 | 0.94 | DHFR (0.54) | DHFR | |
| SCHEMBL6978957 | 0.94 | DHFR (0.56) | DHFR | |
| SCHEMBL6974971 | 0.94 | DHFR (0.56) | DHFR | |
| SCHEMBL13123230 | 0.90 | DHFR (0.51) | DHFR | |
| SCHEMBL1128106 | 0.87 | DHFR (0.53) | DHFR | |
| SCHEMBL13650290 | 0.84 | DHFR (0.56) | DHFR | |
| Ch-1504 SCHEMBL7281 | 0.84 | DHFR (0.65) | DHFR | |
| Ch-1504 SCHEMBL29430185 | 0.84 | DHFR (0.65) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064377-A1 | ANTIFOLATE COMPOSITIONS | CHELSEA THERAPEUTICS, INC. (US) | 2012-05-18 | — | — | WO | disclosed |