Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474946 | 0.77 | CPA1 (0.47) | ALDH1A1CYP1A2 | |
| SCHEMBL2054182 | 0.77 | SLC6A2 (0.49) | CYP3A4CYP2D6 | |
| SCHEMBL14276991 | 0.73 | ALDH1A1 (0.48) | SMN1; SMN2L3MBTL1NPC1RAB9AHSD17B10 | |
| SCHEMBL28306984 | 0.73 | CYP1A2 (0.49) | NPC1RAB9ATSHRALDH1A1MEN1 | |
| SCHEMBL266009 | 0.73 | MEN1 (0.42) | SMN1; SMN2HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL12381771 | 0.72 | MAPT (0.53) | SMN1; SMN2RAB9AHSD17B10TSHRALDH1A1 | |
| SCHEMBL12710192 | 0.71 | L3MBTL1 (0.46) | SMN1; SMN2L3MBTL1NPC1RAB9ATSHR | |
| SCHEMBL1755269 | 0.71 | MAPT (0.51) | SMN1; SMN2RAB9AHSD17B10TSHRALDH1A1 | |
| SCHEMBL15389596 | 0.70 | MAPT (0.47) | SMN1; SMN2L3MBTL1NPC1RAB9AHSD17B10 | |
| SCHEMBL2597758 | 0.70 | TSHR (0.58) | SMN1; SMN2L3MBTL1NPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218343-A4 | PYRIDINE CARBOXAMIDE OR SULFONAMIDE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2003-06-18 | — | — | EP | claimed |
| EP-1218343-A1 | PYRIDINE CARBOXAMIDE OR SULFONAMIDE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-07-03 | — | — | EP | claimed |
| WO-2001025203-A1 | PYRIDINE CARBOXAMIDE OR SULFONAMIDE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-04-12 | — | — | WO | claimed |