Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.58 |
| ▸ | CTSL | P07711 | 8/20 | 0.58 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSB | P07858 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6105981 | 0.86 | CTSS (0.59) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5357750 | 0.80 | CTSL (0.66) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6973028 | 0.79 | CTSS (0.57) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6966191 | 0.78 | CTSS (0.75) | CTSSCTSL | |
| SCHEMBL5362056 | 0.78 | CTSL (0.68) | CTSSCTSLCTSKCTSB | |
| SCHEMBL7418162 | 0.78 | CTSS (0.51) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5365222 | 0.77 | CTSS (0.64) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6108159 | 0.77 | CTSS (0.60) | CTSSCTSLCTSKCTSB | |
| SCHEMBL2568468 | 0.77 | NPC1 (0.38) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5362200 | 0.77 | CTSL (0.84) | CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2003-07-02 | — | — | EP | claimed |