Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975510 | 1.00 | HCAR3 (0.46) | HCAR3MAPTKMT2AALDH1A1MAPK1 | |
| SCHEMBL6975515 | 1.00 | HCAR3 (0.46) | HCAR3MAPTKMT2AALDH1A1MAPK1 | |
| SCHEMBL27530717 | 0.87 | HCAR3 (0.47) | HCAR3MAPTKMT2AALDH1A1MAPK1 | |
| SCHEMBL7421837 | 0.87 | KCNH2 (0.57) | MAPTKMT2AALDH1A1MAPK1NPC1 | |
| SCHEMBL7421839 | 0.87 | KCNH2 (0.57) | MAPTKMT2AALDH1A1MAPK1NPC1 | |
| SCHEMBL8013773 | 0.87 | KCNH2 (0.57) | MAPTKMT2AALDH1A1MAPK1NPC1 | |
| Hydrochloric Acid SCHEMBL11188914 | 0.86 | KCNH2 (0.44) | MAPTKMT2AALDH1A1MAPK1HTT | |
| SCHEMBL11105585 | 0.86 | KCNH2 (0.44) | MAPTKMT2AALDH1A1MAPK1RAB9A | |
| Hydrochloric Acid SCHEMBL11188912 | 0.86 | KCNH2 (0.44) | MAPTKMT2AALDH1A1MAPK1HTT | |
| Hydrochloric Acid SCHEMBL11188921 | 0.86 | KCNH2 (0.44) | MAPTKMT2AALDH1A1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10087650-A | — | — | None | — | — | JP | disclosed |
| EP-0934296-B1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6066631-A | Chroman derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| JP-H1087650-A | CHROMAN DERIVATIVE | NISSAN CHEM IND LTD | 1998-04-07 | — | — | JP | disclosed |