Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421839 | 1.00 | KCNH2 (0.57) | KCNH2PKML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL7421837 | 1.00 | KCNH2 (0.57) | KCNH2PKML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL6975901 | 0.88 | KCNH2 (0.56) | KCNH2PKML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL6975895 | 0.88 | KCNH2 (0.56) | KCNH2PKML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL6975891 | 0.88 | KCNH2 (0.56) | KCNH2PKML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL6975515 | 0.87 | HCAR3 (0.46) | KCNH2PKML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL6975503 | 0.87 | HCAR3 (0.46) | KCNH2PKML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL6975510 | 0.87 | HCAR3 (0.46) | KCNH2PKML3MBTL1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL11188921 | 0.84 | KCNH2 (0.44) | KCNH2ALDH1A1KMT2ALMNAABCB1 | |
| SCHEMBL11105597 | 0.84 | KCNH2 (0.44) | KCNH2PKMALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066631-A | Chroman derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-23 | — | — | US | disclosed |