Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAAO | P46952 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6644861 | 0.78 | TSHR (0.40) | GAATNKSPARP1TNKS2SMN1; SMN2 | |
| SCHEMBL6975538 | 0.77 | RXRA (0.37) | GAATNKSPARP1TNKS2SMN1; SMN2 | |
| SCHEMBL2733549 | 0.74 | TNKS (0.49) | GAATNKSPARP1TNKS2HPGD | |
| SCHEMBL11727757 | 0.73 | RXRA (0.51) | HAAOHPGDRXRARXRBRXRG | |
| Methylpyrrolidone SCHEMBL7756996 | 0.72 | BRD4 (0.47) | HAAOGAATNKSPARP1TNKS2 | |
| SCHEMBL3231655 | 0.72 | RXRA (0.50) | HAAOGAAHPGDRXRARXRB | |
| SCHEMBL6643060 | 0.71 | NOTUM (0.44) | GAAPARP1SMN1; SMN2RXRARXRB | |
| SCHEMBL251512 | 0.70 | CYP1A2 (0.57) | GAAHPGDSMN1; SMN2RXRARXRB | |
| SCHEMBL87519 | 0.70 | CYP1A2 (0.57) | GAAHPGDSMN1; SMN2RXRARXRB | |
| SCHEMBL19007350 | 0.69 | HTR2C (0.43) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931070-B1 | HETAROYL CYCLOHEXANEDIONE DERIVATIVES WITH HERBICIDAL EFFECT | BASF AG (DE) | 2003-03-19 | — | — | EP | disclosed |
| US-6479436-B1 | SUCH AS 2-(8-BROMOQUINOLIN-5-YL)CARBONYL-1,3-CYCLOHEXANEDIONE | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-12 | — | — | US | disclosed |
| US-6262074-B1 | 4-Hetaroylpyrazol derivatives and the use thereof as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-17 | — | — | US | disclosed |
| CN-1235600-A | 4-hetaroylpyrazol derivatives | BASF AG (DE) | 1999-11-17 | — | — | CN | disclosed |
| CN-1230951-A | Herbicidal heteroaroyl cyclohexanedione derivatives | BASF AG (DE) | 1999-10-06 | — | — | CN | disclosed |
| EP-0931070-A1 | HETAROYL CYCLOHEXANEDIONE DERIVATIVES WITH HERBICIDAL EFFECT | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998012180-A1 | HETAROYL CYCLOHEXANEDIONE DERIVATIVES WITH HERBICIDAL EFFECT | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-26 | — | — | WO | disclosed |