Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.37 |
| ▸ | RXRB | P28702 | 4/20 | 0.37 |
| ▸ | RXRG | P48443 | 4/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975536 | 0.77 | HAAO (0.38) | RXRARXRBRXRGTNKSPARP1 | |
| SCHEMBL19178086 | 0.69 | RXRA (0.33) | RXRARXRBRXRGKDM4EALDH1A1 | |
| SCHEMBL6970156 | 0.69 | KDM4E (0.37) | RXRARXRBRXRGPARP1KDM4E | |
| SCHEMBL19007350 | 0.66 | HTR2C (0.43) | — | |
| SCHEMBL983662 | 0.64 | PTPN1 (0.45) | SMN1; SMN2KDM4EALDH1A1TSHRL3MBTL1 | |
| SCHEMBL1709095 | 0.64 | HSD17B10 (0.35) | PARP1KDM4EALDH1A1TSHRL3MBTL1 | |
| SCHEMBL22057586 | 0.63 | RXRA (0.50) | RXRARXRBRXRGKDM4EALDH1A1 | |
| SCHEMBL13184286 | 0.63 | INMT (0.38) | PARP1 | |
| SCHEMBL6644861 | 0.63 | TSHR (0.40) | TNKSPARP1TNKS2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7873208 | 0.62 | MEN1 (0.52) | SMN1; SMN2KDM4EALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931070-B1 | HETAROYL CYCLOHEXANEDIONE DERIVATIVES WITH HERBICIDAL EFFECT | BASF AG (DE) | 2003-03-19 | — | — | EP | disclosed |
| EP-0931070-A1 | HETAROYL CYCLOHEXANEDIONE DERIVATIVES WITH HERBICIDAL EFFECT | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998012180-A1 | HETAROYL CYCLOHEXANEDIONE DERIVATIVES WITH HERBICIDAL EFFECT | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-26 | — | — | WO | disclosed |