Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68599 | 0.75 | ACHE (0.43) | GPR3BRD4 | |
| SCHEMBL7818214 | 0.73 | BRD4 (0.40) | GPR3BRD4 | |
| Hydrochloric Acid SCHEMBL8493531 | 0.72 | ACHE (0.44) | GPR3 | |
| SCHEMBL13354911 | 0.64 | CRBN (0.46) | BRD4 | |
| SCHEMBL9416572 | 0.59 | ELANE (0.43) | — | |
| SCHEMBL20794244 | 0.59 | IDH1 (0.32) | — | |
| SCHEMBL8779728 | 0.59 | — | — | |
| SCHEMBL17288993 | 0.58 | — | — | |
| SCHEMBL20826195 | 0.58 | MAOA (0.47) | — | |
| SCHEMBL13027943 | 0.58 | CLK4 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131321-B1 | INDOLE DERIVATIVES AND THEIR USE AS SEROTONIN RECEPTOR LIGANDS | LILLY CO ELI (GB) | 2003-09-10 | — | — | EP | disclosed |
| EP-1131321-A2 | INDOLE DERIVATIVES AND THEIR USE AS SEROTONIN RECEPTOR LIGANDS | ELI LILLY AND COMPANY LIMITED (GB) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000031074-A2 | INDOLE DERIVATIVES AND THEIR USE AS SEROTONIN RECEPTOR LIGANDS | ELI LILLY AND COMPANY LIMITED (GB) | 2000-06-02 | — | — | WO | disclosed |