Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971751 | 0.96 | CNR2 (0.41) | HTR6CNR2MAPTKMT2AACHE | |
| SCHEMBL6967847 | 0.88 | ALDH1A1 (0.45) | HTR6CNR2MAPTKMT2AACHE | |
| SCHEMBL6967992 | 0.84 | HTR6 (0.39) | HTR6MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6965248 | 0.84 | CNR2 (0.46) | HTR6CNR2MAPTKMT2AACHE | |
| SCHEMBL6971803 | 0.83 | HTR6 (0.41) | HTR6MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6972954 | 0.82 | HTR6 (0.42) | HTR6CNR2MAPTKMT2AACHE | |
| SCHEMBL6977194 | 0.82 | HTR6 (0.45) | HTR6MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6975027 | 0.82 | HTR6 (0.45) | HTR6MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6967417 | 0.81 | HTR6 (0.41) | HTR6MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6971624 | 0.81 | HTR6 (0.41) | HTR6MAPTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |