Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975816 | 1.00 | KMT2A (0.37) | KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6977597 | 0.76 | IDH1 (0.30) | — | |
| SCHEMBL14456031 | 0.75 | PIK3CD (0.32) | — | |
| SCHEMBL765766 | 0.75 | PIK3CD (0.32) | — | |
| SCHEMBL6964149 | 0.73 | KMT2A (0.36) | KMT2AALDH1A1MAPT | |
| SCHEMBL6971327 | 0.73 | KMT2A (0.36) | KMT2AALDH1A1MAPT | |
| SCHEMBL6964143 | 0.73 | KMT2A (0.36) | KMT2AALDH1A1MAPT | |
| SCHEMBL6977046 | 0.72 | IDH1 (0.32) | — | |
| SCHEMBL6977048 | 0.72 | IDH1 (0.32) | — | |
| SCHEMBL6977600 | 0.72 | CRBN (0.37) | KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023265-B1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM CA LTD (CA) | 2003-01-15 | — | — | EP | disclosed |
| US-6211170-B1 | Azetidinone derivatives for the treatment of HCMV infections | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-04-03 | — | — | US | disclosed |