Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975816 | 0.76 | KMT2A (0.37) | — | |
| SCHEMBL6975819 | 0.76 | KMT2A (0.37) | — | |
| SCHEMBL14456031 | 0.74 | PIK3CD (0.32) | IDH1 | |
| SCHEMBL765766 | 0.74 | PIK3CD (0.32) | IDH1 | |
| SCHEMBL6977046 | 0.71 | IDH1 (0.32) | IDH1 | |
| SCHEMBL6977048 | 0.71 | IDH1 (0.32) | IDH1 | |
| SCHEMBL6977778 | 0.70 | NPC1 (0.31) | — | |
| SCHEMBL11093784 | 0.68 | — | — | |
| SCHEMBL10414801 | 0.68 | MAPT (0.33) | — | |
| SCHEMBL10540453 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023265-B1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM CA LTD (CA) | 2003-01-15 | — | — | EP | disclosed |
| US-6211170-B1 | Azetidinone derivatives for the treatment of HCMV infections | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-04-03 | — | — | US | disclosed |