Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964149 | 1.00 | KMT2A (0.36) | KMT2AALDH1A1TSHRMAPTTDP1 | |
| SCHEMBL6964143 | 1.00 | KMT2A (0.36) | KMT2AALDH1A1TSHRMAPTTDP1 | |
| SCHEMBL7388011 | 0.76 | KMT2A (0.35) | KMT2AALDH1A1MAPTTDP1PKM | |
| SCHEMBL6975819 | 0.73 | KMT2A (0.37) | KMT2AALDH1A1MAPT | |
| SCHEMBL6975816 | 0.73 | KMT2A (0.37) | KMT2AALDH1A1MAPT | |
| SCHEMBL6977778 | 0.72 | NPC1 (0.31) | KMT2AALDH1A1 | |
| SCHEMBL247623 | 0.71 | MAPT (0.40) | KMT2AMAPT | |
| SCHEMBL6970938 | 0.69 | KMT2A (0.42) | KMT2AALDH1A1TSHR | |
| SCHEMBL14156180 | 0.65 | LMNA (0.56) | KMT2AALDH1A1MAPTTDP1PKM | |
| SCHEMBL6978352 | 0.63 | KMT2A (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023265-B1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM CA LTD (CA) | 2003-01-15 | — | — | EP | disclosed |
| US-6211170-B1 | Azetidinone derivatives for the treatment of HCMV infections | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-04-03 | — | — | US | disclosed |