Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965870 | 0.87 | ALDH1A1 (0.33) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL6972910 | 0.72 | ALDH1A1 (0.35) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL6966584 | 0.72 | MEN1 (0.37) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL8345126 | 0.68 | MEN1 (0.33) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL7081639 | 0.67 | ALOX12 (0.38) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL7078163 | 0.66 | MEN1 (0.38) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL6966591 | 0.66 | USP7 (0.32) | USP7ALOX5 | |
| SCHEMBL6975849 | 0.65 | ALOX12 (0.34) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL6961234 | 0.64 | TYMS (0.34) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL8346906 | 0.64 | MEN1 (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |