Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 7/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975870 | 0.87 | SMN1; SMN2 (0.48) | CNR1CAMK2DPIM1CCNT1CDK9 | |
| Acetic Acid SCHEMBL7679495 | 0.85 | F2RL3 (0.47) | CNR1CAMK2DPIM1CCNT1CDK9 | |
| SCHEMBL6980479 | 0.83 | CAMK2D (0.45) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| Acetic Acid SCHEMBL6983431 | 0.82 | CAMK2D (0.48) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL6975973 | 0.82 | CAMK2D (0.53) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL6977746 | 0.82 | CAMK2D (0.51) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL6980034 | 0.80 | CCNT1 (0.48) | CNR1CAMK2DPIM1CCNT1CDK9 | |
| Trifluoroacetic Acid SCHEMBL6985258 | 0.80 | CAMK2D (0.39) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL6985899 | 0.79 | MAPT (0.40) | CNR1CCNT1CDK9CCNA2CDK2 | |
| SCHEMBL6977406 | 0.79 | CAMK2D (0.56) | CAMK2DPIM1CCNT1CDK9RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095039-B1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-27 | — | — | EP | claimed |
| US-6346625-B1 | ENZYME INHIBITORS FOR PROTEIN KINASES | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | claimed |
| EP-1095039-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2001-05-02 | — | — | EP | claimed |
| WO-2000002877-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | claimed |
| EP-1095039-B1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-27 | — | — | EP | disclosed |
| US-6346625-B1 | ENZYME INHIBITORS FOR PROTEIN KINASES | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | disclosed |
| EP-1095039-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002877-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | disclosed |