Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975895 | 1.00 | KCNH2 (0.56) | KCNH2L3MBTL1PKMLMNAMAPT | |
| SCHEMBL6975891 | 1.00 | KCNH2 (0.56) | KCNH2L3MBTL1PKMLMNAMAPT | |
| SCHEMBL8013773 | 0.88 | KCNH2 (0.57) | KCNH2L3MBTL1PKMLMNAMAPT | |
| SCHEMBL7421839 | 0.88 | KCNH2 (0.57) | KCNH2L3MBTL1PKMLMNAMAPT | |
| SCHEMBL7421837 | 0.88 | KCNH2 (0.57) | KCNH2L3MBTL1PKMLMNAMAPT | |
| SCHEMBL27530717 | 0.86 | HCAR3 (0.47) | KCNH2MAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6980817 | 0.82 | KCNH2 (0.56) | KCNH2L3MBTL1PKMLMNAMAPT | |
| SCHEMBL6581308 | 0.79 | KCNH2 (0.68) | KCNH2L3MBTL1PKMLMNAMAPT | |
| SCHEMBL6581297 | 0.79 | KCNH2 (0.68) | KCNH2L3MBTL1PKMLMNAMAPT | |
| SCHEMBL6581304 | 0.79 | KCNH2 (0.68) | KCNH2L3MBTL1PKMLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934296-B1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6066631-A | Chroman derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-23 | — | — | US | disclosed |