Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.57 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976350 | 0.89 | PTGS2 (0.61) | PTGS2RETPTGS1NTRK1PLK3 | |
| SCHEMBL6979358 | 0.86 | PTGS2 (0.67) | PTGS2RETPTGS1CA1CA2 | |
| SCHEMBL6981487 | 0.85 | PTGS2 (0.62) | PTGS2RETPTGS1CA1CA2 | |
| SCHEMBL6976262 | 0.84 | PTGS2 (0.59) | PTGS2RETPTGS1MAPK14 | |
| SCHEMBL6979031 | 0.83 | PTGS2 (0.61) | PTGS2RETPTGS1NTRK1PLK3 | |
| SCHEMBL6972219 | 0.83 | PTGS2 (0.66) | PTGS2PTGS1MAPK14 | |
| SCHEMBL6981445 | 0.83 | PTGS2 (0.63) | PTGS2PTGS1MAPK14 | |
| SCHEMBL6974299 | 0.81 | PTGS2 (0.67) | PTGS2PTGS1NTRK1PLK3MAPK14 | |
| SCHEMBL6972161 | 0.81 | PTGS2 (0.58) | PTGS2RETPTGS1NTRK1PLK3 | |
| SCHEMBL6973002 | 0.81 | PTGS2 (0.55) | PTGS2RETPTGS1NTRK1PLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | claimed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | claimed |
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | disclosed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | disclosed |
| EP-1105384-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010993-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2000-03-02 | — | — | WO | disclosed |