Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976262 | 0.92 | PTGS2 (0.59) | PTGS2MAPK14PLA2G2APLA2G4ARET | |
| SCHEMBL6979358 | 0.91 | PTGS2 (0.67) | PTGS2MAPK14PLA2G2APLA2G4ARET | |
| SCHEMBL6972219 | 0.88 | PTGS2 (0.66) | PTGS2MAPK14PLA2G2APLA2G4APTGS1 | |
| SCHEMBL6973940 | 0.88 | PTGS2 (0.69) | PTGS2MAPK14PLA2G2APLA2G4ARET | |
| SCHEMBL6981445 | 0.88 | PTGS2 (0.63) | PTGS2MAPK14PTGS1 | |
| SCHEMBL6974845 | 0.87 | PTGS2 (0.72) | PTGS2MAPK14PLA2G2APLA2G4APTGS1 | |
| SCHEMBL6974187 | 0.87 | PTGS2 (0.72) | PTGS2MAPK14PLA2G2APLA2G4APTGS1 | |
| SCHEMBL6976779 | 0.86 | PTGS2 (0.67) | PTGS2MAPK14PLA2G2APLA2G4APTGS1 | |
| SCHEMBL6976428 | 0.85 | PTGS2 (0.57) | PTGS2MAPK14RETPTGS1CA1 | |
| SCHEMBL6977227 | 0.85 | PTGS2 (0.63) | PTGS2MAPK14PLA2G2APLA2G4APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | claimed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | claimed |
| EP-1105384-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2001-06-13 | — | — | EP | claimed |
| WO-2000010993-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2000-03-02 | — | — | WO | claimed |
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | disclosed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | disclosed |
| EP-1105384-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010993-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2000-03-02 | — | — | WO | disclosed |