Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7943658 | 0.91 | PPARA (0.51) | KMT2ASMN1; SMN2PPARAPPARGHPGD | |
| SCHEMBL13120939 | 0.84 | SMN1; SMN2 (0.53) | KMT2ASMN1; SMN2PPARAPPARGKDM4E | |
| SCHEMBL12545943 | 0.81 | PPARA (0.56) | KMT2ASMN1; SMN2PPARAPPARGHPGD | |
| SCHEMBL20546749 | 0.80 | PTGS1 (0.52) | KMT2ASMN1; SMN2HPGDF10FFAR1 | |
| SCHEMBL31109331 | 0.80 | PTGS1 (0.52) | KMT2ASMN1; SMN2HPGDF10FFAR1 | |
| SCHEMBL9863137 | 0.79 | PPARA (0.67) | SMN1; SMN2PPARAPPARGHPGDKDM4E | |
| SCHEMBL27583460 | 0.79 | PPARA (0.57) | KMT2APPARAPPARGHPGDKDM4E | |
| SCHEMBL13724830 | 0.79 | L3MBTL1 (0.55) | KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15245059 | 0.79 | LMNA (0.56) | KMT2ASMN1; SMN2PPARAPPARGFFAR1 | |
| SCHEMBL5720924 | 0.78 | KMT2A (0.66) | KMT2ASMN1; SMN2FFAR1LMNACTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-1098878-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000003986-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |