Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377265 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6975634 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6977125 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5708993 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5708933 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6975614 | 0.82 | PTGS2 (0.83) | PTGS2PTGS1 | |
| SCHEMBL6972681 | 0.81 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL7259692 | 0.80 | PTGS2 (0.67) | PTGS2 | |
| SCHEMBL6968964 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6974584 | 0.79 | PTGS2 (0.78) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115716-B1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | ALMIRALL PRODESFARMA AG (CH) | 2003-01-02 | — | — | EP | disclosed |
| US-20020045644-A1 | 2-phenylpyran-4-one derivatives | LABORATORIES ALMIRALL, S.A. (ES) | 2002-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045644-A1 | 2-phenylpyran-4-one derivatives | NR4A1, CYP3A4, HTR4 | PTGS2 912/4885PTGS1 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.