Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246480 | 0.87 | NR1H2 (0.41) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL6217654 | 0.87 | HPGD (0.40) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3244534 | 0.87 | NR1H2 (0.41) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5186931 | 0.85 | MEN1 (0.39) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL426434 | 0.85 | NR1H2 (0.39) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL6977617 | 0.85 | MEN1 (0.39) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL427722 | 0.83 | EPHX1 (0.38) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL19895485 | 0.83 | GPR119 (0.39) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL447284 | 0.83 | EPHX1 (0.38) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL25205542 | 0.83 | HPGD (0.48) | HPGDMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051413-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-04 | — | — | EP | disclosed |
| EP-1051413-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037635-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1999-07-29 | — | — | WO | disclosed |