Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186931 | 1.00 | MEN1 (0.39) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL427722 | 0.88 | EPHX1 (0.38) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL447284 | 0.88 | EPHX1 (0.38) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL3246480 | 0.88 | NR1H2 (0.41) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL6217654 | 0.88 | HPGD (0.40) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL3244534 | 0.88 | NR1H2 (0.41) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL426434 | 0.85 | NR1H2 (0.39) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL6976635 | 0.85 | HPGD (0.42) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL5304979 | 0.81 | RECQL (0.39) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL19895485 | 0.79 | GPR119 (0.39) | MEN1ALDH1A1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051413-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-04 | — | — | EP | disclosed |
| EP-1051413-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037635-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1999-07-29 | — | — | WO | disclosed |