Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26758995 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL18641395 | 0.76 | HDAC8 (0.37) | HDAC8CYP17A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL441788 | 0.75 | — | — | |
| SCHEMBL25627108 | 0.73 | HDAC8 (0.32) | HDAC8 | |
| SCHEMBL18622148 | 0.73 | — | — | |
| SCHEMBL28111832 | 0.68 | CYP17A1 (0.36) | HDAC8CYP17A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7509467 | 0.68 | TAAR1 (0.45) | TAAR1 | |
| SCHEMBL27817636 | 0.68 | — | — | |
| SCHEMBL19575790 | 0.68 | HTR1A (0.33) | — | |
| SCHEMBL15979325 | 0.67 | ALOX5 (0.30) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088181-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2011-07-21 | — | — | WO | disclosed |