Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | F13A1 | P00488 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099654 | 0.89 | CA2 (0.48) | KDM4EF13A1CA2TMEM97SIGMAR1 | |
| SCHEMBL25004248 | 0.85 | GFER (0.46) | KDM4ECA2CA1TAAR1GFER | |
| SCHEMBL4462532 | 0.84 | KDM4E (0.55) | KDM4ECA2CA1TAAR1ALDH1A1 | |
| SCHEMBL4452224 | 0.84 | IDO1 (0.54) | CA2CA1CYP2C19TAAR1L3MBTL1 | |
| SCHEMBL4344215 | 0.83 | TAAR1 (0.54) | KDM4ECA2CA1SIGMAR1CYP2C19 | |
| SCHEMBL288827 | 0.83 | KDM4E (0.55) | KDM4EF13A1CA2CA1TMEM97 | |
| SCHEMBL26292919 | 0.81 | KDM4E (0.62) | KDM4EF13A1CA2CA1TMEM97 | |
| SCHEMBL11273783 | 0.81 | CA2 (0.55) | CA2CA1GFERBLM | |
| SCHEMBL69319 | 0.81 | TAAR1 (0.52) | KDM4ECA2CA1SIGMAR1CYP2C19 | |
| SCHEMBL4459745 | 0.80 | SMN1; SMN2 (0.59) | KDM4ECA2CA1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282418-A2 | USE OF PYRAZOLE DERIVATIVES FOR TREATING INFERTILITY | Serono Reproductive Biology Institute, Inc. (US) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087287-A2 | USE OF PYRAZOLE DERIVATIVES FOR TREATING INFERTILITY | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-11-22 | — | — | WO | disclosed |