Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 9/20 | 0.44 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975119 | 1.00 | PIM1 (0.47) | PIM1PIM2PPARGHPGDCISD1 | |
| SCHEMBL6963266 | 0.86 | HPGD (0.51) | PPARGHPGD | |
| SCHEMBL6963373 | 0.86 | HPGD (0.51) | PPARGHPGD | |
| SCHEMBL6966002 | 0.81 | PPARG (0.49) | PPARGHPGD | |
| SCHEMBL6966624 | 0.79 | PPARG (0.47) | PIM1PIM2PPARGHPGDCISD1 | |
| SCHEMBL6966626 | 0.79 | PPARG (0.47) | PIM1PIM2PPARGHPGDCISD1 | |
| SCHEMBL6968233 | 0.78 | PPARG (0.47) | PIM1PIM2PPARGHPGDCISD1 | |
| SCHEMBL6968236 | 0.78 | PPARG (0.47) | PIM1PIM2PPARGHPGDCISD1 | |
| SCHEMBL8305155 | 0.77 | HPGD (0.46) | PIM1PIM2HPGDPARP1 | |
| SCHEMBL6969819 | 0.77 | HPGD (0.46) | PIM1PIM2HPGDPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801063-B1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2003-01-15 | — | — | EP | claimed |