Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963373 | 1.00 | HPGD (0.51) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL6968430 | 0.87 | MCHR1 (0.37) | MAOB | |
| SCHEMBL6975119 | 0.86 | PIM1 (0.47) | HPGDPPARG | |
| SCHEMBL6976890 | 0.86 | PIM1 (0.47) | HPGDPPARG | |
| SCHEMBL6969588 | 0.83 | PPARG (0.47) | HPGDPPARGMEN1KMT2A | |
| SCHEMBL6981132 | 0.83 | RAB9A (0.39) | MAOAMAOB | |
| SCHEMBL6968820 | 0.81 | KCNH2 (0.44) | MAOBMEN1KMT2A | |
| SCHEMBL6967865 | 0.81 | HPGD (0.51) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL6967873 | 0.81 | HPGD (0.51) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL6967821 | 0.80 | HPGD (0.50) | HPGDPTPN1MAOAMAOBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801063-B1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2003-01-15 | — | — | EP | claimed |
| EP-0801063-B1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2003-01-15 | — | — | EP | disclosed |
| EP-0801063-A1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-10-15 | — | — | EP | disclosed |