Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.54 |
| ▸ | FLT3 | P36888 | 4/20 | 0.52 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ME3 | Q16798 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962399 | 0.90 | NPY5R (0.68) | NPY5RFLT3MALT1USP30AURKA | |
| SCHEMBL6960814 | 0.84 | FAAH (0.56) | NPY5RFLT3AURKAKDRMAPT | |
| SCHEMBL6967662 | 0.83 | NPY5R (0.71) | NPY5RFLT3USP30KDR | |
| SCHEMBL6998436 | 0.82 | NPY5R (0.79) | NPY5RFLT3USP30MAPTNPC1 | |
| SCHEMBL6962480 | 0.78 | NPY5R (0.63) | NPY5RMAPT | |
| SCHEMBL6968019 | 0.74 | NPY5R (0.67) | NPY5RFLT3AURKAKDRMAPT | |
| SCHEMBL26396572 | 0.73 | GSK3A (0.53) | MALT1 | |
| SCHEMBL6963922 | 0.72 | FAAH (0.58) | NPY5RFLT3AURKAKDRMAPT | |
| Hydrochloric Acid SCHEMBL26128044 | 0.72 | GSK3A (0.53) | MALT1 | |
| SCHEMBL6959291 | 0.72 | FAAH (0.66) | NPY5RFLT3AURKAKDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945439-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |
| US-6166038-A | Aminopyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | claimed |
| EP-0945439-A1 | NOVEL AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945439-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-6166038-A | Aminopyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0945439-A1 | NOVEL AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |