Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967662 | 0.91 | NPY5R (0.71) | NPY5RCHRNA3KCNH2CSNK2A2CSNK2A1 | |
| SCHEMBL6961328 | 0.86 | MAPT (0.56) | NPY5RMAPTCHRNA3KCNH2THRB | |
| SCHEMBL6962399 | 0.83 | NPY5R (0.68) | NPY5RMAPT | |
| SCHEMBL6991250 | 0.80 | NPY5R (0.79) | NPY5RCHRNA3KCNH2CSNK2A2CSNK2A1 | |
| SCHEMBL6993059 | 0.78 | NPY5R (0.80) | NPY5RCHRNA3KCNH2CSNK2A2CSNK2A1 | |
| SCHEMBL7000363 | 0.78 | NPY5R (1.00) | NPY5RCHRNA3KCNH2CSNK2A2CSNK2A1 | |
| SCHEMBL6976896 | 0.78 | NPY5R (0.54) | NPY5RMAPT | |
| SCHEMBL6956624 | 0.76 | NPY5R (0.58) | NPY5RMAPTCHRNA3KCNH2CSNK2A2 | |
| SCHEMBL6959277 | 0.75 | RBP4 (0.53) | NPY5RMAPTTHRBLMNA | |
| SCHEMBL6996444 | 0.74 | NPY5R (0.86) | NPY5RCHRNA3KCNH2CSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945439-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |
| US-6166038-A | Aminopyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | claimed |
| EP-0945439-A1 | NOVEL AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945439-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-6166038-A | Aminopyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0945439-A1 | NOVEL AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |