Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 9/20 | 0.38 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980061 | 0.85 | KCNJ1 (0.47) | TP53HRH3MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL6975443 | 0.81 | TP53 (0.54) | TP53MAPK1NPC1MAPTRAB9A | |
| SCHEMBL6977058 | 0.80 | FFAR1 (0.36) | KDM1AYAP1MAPK1SMN1; SMN2KCNJ1 | |
| SCHEMBL6974883 | 0.80 | TP53 (0.41) | TP53KDM1AMAPK1NPC1MAPT | |
| SCHEMBL6985046 | 0.79 | KMT2A (0.43) | MAPK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6979722 | 0.79 | TP53 (0.48) | TP53MAPK1NPC1MAPTRAB9A | |
| SCHEMBL7959087 | 0.79 | TP53 (0.48) | TP53MAPK1NPC1MAPTRAB9A | |
| SCHEMBL7410530 | 0.69 | TP53 (0.45) | TP53KDM1AALDH1A1 | |
| SCHEMBL6985050 | 0.69 | ALDH1A1 (0.39) | YAP1NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL6986432 | 0.68 | TP53 (0.48) | TP53MAPK1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |