Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 5/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985050 | 0.80 | ALDH1A1 (0.39) | YAP1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL6977052 | 0.80 | TP53 (0.39) | KDM1AYAP1SMN1; SMN2KCNJ1KCNH2 | |
| SCHEMBL6974890 | 0.78 | DPP8 (0.37) | FFAR1KDM1AYAP1HPGDSMN1; SMN2 | |
| SCHEMBL6979727 | 0.78 | TSHR (0.40) | FFAR1HPGDSMN1; SMN2KCNJ1KCNH2 | |
| SCHEMBL6980061 | 0.73 | KCNJ1 (0.47) | FFAR1HPGDSMN1; SMN2KCNJ1KCNH2 | |
| SCHEMBL6985046 | 0.70 | KMT2A (0.43) | SMN1; SMN2ALDH1A1MAPK1HTR2AMEN1 | |
| SCHEMBL6974883 | 0.69 | TP53 (0.41) | FFAR1KDM1ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7410532 | 0.69 | CHRM2 (0.41) | KDM1AYAP1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL6986713 | 0.68 | TSHR (0.41) | FFAR1HPGDKCNJ1KCNH2ALDH1A1 | |
| SCHEMBL6986437 | 0.67 | PTGER4 (0.41) | FFAR1HPGDSMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |