Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | USP14 | P54578 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7401529 | 0.89 | PLG (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7948828 | 0.79 | ITK (0.45) | TP53MEN1KMT2AHDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL6985560 | 0.78 | F2 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6983536 | 0.78 | TP53 (0.43) | TP53MEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL6985246 | 0.77 | TP53 (0.51) | TP53MEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL6986538 | 0.76 | TP53 (0.49) | TP53MEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL6979174 | 0.76 | TP53 (0.50) | TP53MEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL6981826 | 0.75 | PDK1 (0.52) | TP53MEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL7959057 | 0.75 | PDK1 (0.41) | TP53MEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL6977731 | 0.75 | TP53 (0.45) | TP53MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |