Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631291 | 0.82 | NOS1 (0.39) | ALDH1A1SLC18A3PRCP | |
| SCHEMBL4870454 | 0.71 | MAPT (0.39) | GID4SLC18A3MAPTGFERCYP1A2 | |
| SCHEMBL4871362 | 0.71 | MAPT (0.39) | GID4SLC18A3MAPTGFERCYP1A2 | |
| SCHEMBL3717223 | 0.71 | MEN1 (0.51) | GID4SMN1; SMN2MAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4912494 | 0.70 | MAPT (0.38) | GID4SLC18A3MAPTGFERCYP19A1 | |
| SCHEMBL14458009 | 0.69 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTKMT2ANPC1 | |
| SCHEMBL22201146 | 0.69 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTKMT2ANPC1 | |
| SCHEMBL8541954 | 0.69 | MEN1 (0.50) | GID4SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7672102 | 0.69 | MEN1 (0.50) | GID4SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7992297 | 0.68 | MKNK1 (0.55) | SMN1; SMN2MAPTKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |