Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298007 | 0.84 | RAB9A (0.79) | RAB9ASMN1; SMN2MAPTKMT2AHSD17B10 | |
| SCHEMBL11456649 | 0.81 | RAB9A (0.68) | RAB9ASMN1; SMN2MAPTKMT2AHSD17B10 | |
| SCHEMBL15923472 | 0.81 | RAB9A (0.72) | RAB9ASMN1; SMN2MAPTKMT2AHSD17B10 | |
| SCHEMBL10050510 | 0.80 | RAB9A (0.85) | RAB9ASMN1; SMN2MAPTKMT2AHSD17B10 | |
| SCHEMBL5631833 | 0.80 | RAB9A (0.77) | RAB9ASMN1; SMN2MAPTKMT2AHSD17B10 | |
| SCHEMBL7299163 | 0.80 | RAB9A (1.00) | RAB9ASMN1; SMN2MAPTKMT2AHSD17B10 | |
| SCHEMBL9798847 | 0.80 | GAA (0.64) | RAB9ASMN1; SMN2MAPTKMT2AHSD17B10 | |
| SCHEMBL4903484 | 0.79 | RAB9A (0.65) | RAB9ASMN1; SMN2MAPTKMT2AHSD17B10 | |
| SCHEMBL16718938 | 0.79 | RAB9A (0.65) | RAB9ASMN1; SMN2MAPTKMT2AHSD17B10 | |
| SCHEMBL11000826 | 0.79 | ALDH1A1 (0.63) | RAB9ASMN1; SMN2KMT2AHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208092-A4 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO LTD (KR) | 2003-01-02 | — | — | EP | disclosed |
| EP-1208092-A1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001077092-A1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2001-10-18 | — | — | WO | disclosed |