Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | HTR2B | P41595 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5172972 | 0.88 | CALM1 (0.44) | HTR2CHTR2BHTR2ACALM1HRH1 | |
| SCHEMBL2045801 | 0.77 | CALM1 (0.55) | CALM1HRH1LMNA | |
| SCHEMBL1829354 | 0.77 | CALM1 (0.55) | CALM1TAAR1 | |
| SCHEMBL6604926 | 0.75 | HTR2C (0.50) | HTR2CHTR2BHTR2ACALM1HRH1 | |
| SCHEMBL2051544 | 0.74 | CALM1 (0.52) | CALM1HRH1 | |
| SCHEMBL6586984 | 0.74 | CALM1 (0.52) | CALM1HRH1 | |
| SCHEMBL1829180 | 0.74 | CALM1 (0.52) | CALM1HRH1 | |
| Diphenylmethane SCHEMBL27486979 | 0.72 | CALM1 (0.50) | CALM1HRH1GBA1TAAR1 | |
| SCHEMBL2973782 | 0.71 | CALM1 (0.61) | HTR2ACALM1LMNACYP1A2ADRA2A | |
| SCHEMBL14704890 | 0.70 | SIGMAR1 (0.43) | HTR2CHTR2BHTR2ACALM1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1285655-A1 | STABILIZED PHARMACEUTICAL COMPOSITIONS CONTAINING CALCIUM CHANNEL BLOCKERS | Sankyo Company, Limited (JP) | 2003-02-26 | — | — | EP | disclosed |