Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | GABRP | O00591 | 4/20 | 0.58 |
| ▸ | GABRD | O14764 | 4/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.58 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.58 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981850 | 0.89 | GABRP (0.76) | MAOBKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL15231231 | 0.81 | MAOB (0.77) | MAOBKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6974228 | 0.81 | RAB9A (1.00) | MAOBKDM4EALDH1A1HPGDSMN1; SMN2 | |
| 7-Fluoroflavone SCHEMBL12961037 | 0.81 | MAOB (1.00) | MAOBKDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL30674786 | 0.76 | MAOB (1.00) | MAOBKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9142214 | 0.76 | MAOB (1.00) | MAOBKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23804650 | 0.75 | MAOB (0.82) | MAOBKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22083761 | 0.75 | QPCT (0.67) | MAOBKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29114175 | 0.74 | MAOB (0.62) | MAOBKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30626961 | 0.74 | MAOB (0.62) | MAOBKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | disclosed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | disclosed |
| EP-1105384-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010993-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2000-03-02 | — | — | WO | disclosed |