Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 9/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.57 |
| ▸ | CYP24A1 | Q07973 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949630 | 0.87 | CYP19A1 (0.61) | CYP17A1CYP19A1CYP24A1MEN1NR1I2 | |
| SCHEMBL27565980 | 0.84 | CYP17A1 (0.61) | CYP17A1CYP19A1CYP24A1MEN1NR1I2 | |
| SCHEMBL4578052 | 0.84 | CYP17A1 (0.83) | CYP17A1CYP19A1CYP24A1MEN1NR1I2 | |
| SCHEMBL7276614 | 0.84 | CYP17A1 (0.61) | CYP17A1CYP19A1CYP24A1MEN1NR1I2 | |
| SCHEMBL27484897 | 0.81 | CYP17A1 (0.63) | CYP17A1CYP19A1CYP24A1MEN1NR1I2 | |
| SCHEMBL9910964 | 0.81 | CYP17A1 (0.84) | CYP17A1CYP19A1CYP24A1MEN1NR1I2 | |
| SCHEMBL8156789 | 0.81 | CYP19A1 (0.66) | CYP17A1CYP19A1 | |
| SCHEMBL28747929 | 0.80 | CYP17A1 (0.60) | CYP17A1CYP19A1CYP24A1MEN1NR1I2 | |
| SCHEMBL28844444 | 0.80 | CYP17A1 (0.57) | CYP17A1CYP19A1CYP24A1MEN1NR1I2 | |
| SCHEMBL5821117 | 0.80 | CYP19A1 (0.61) | CYP17A1CYP19A1CYP24A1MEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199530-A1 | New compounds derived from quinazoline | LES LABORATORIES SERVIER (FR) | 2003-10-23 | — | — | US | disclosed |
| CN-1445226-A | New cornpound derivated from quinazoline, itd preparation method and medicinal composite containig them | ADIR (FR) | 2003-10-01 | — | — | CN | disclosed |
| EP-1346992-A1 | Quinazoline derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199530-A1 | New compounds derived from quinazoline | NQO2, XDH, DRD1 | CYP17A1 3127/4885CYP19A1 1823/4885CYP24A1 2355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.