SCHEMBL11214315

SCHEMBL11214315

ClCC(c1ccccc1)n1ccnc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.61
CYP17A1 P05093 10/20 0.59
MEN1 O00255 1/20 0.53
NR1I2 O75469 1/20 0.53
USP2 O75604 1/20 0.53
ABCB11 O95342 1/20 0.53
ALDH1A1 P00352 1/20 0.53
PLA2G1B P04054 1/20 0.53
TP53 P04637 1/20 0.53
PGR P06401 1/20 0.53
HSP90AA1 P07900 1/20 0.53
CYP3A4 P08684 1/20 0.53
MAPT P10636 1/20 0.53
IDO1 P14902 1/20 0.53
HPGD P15428 1/20 0.53
MAOA P21397 1/20 0.53
CNR1 P21554 1/20 0.53
HTR2A P28223 1/20 0.53
MAPK1 P28482 1/20 0.53
ADRA1A P35348 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6949630 0.83 CYP19A1 (0.61) CYP19A1CYP17A1MEN1NR1I2USP2
SCHEMBL5297627 0.83 CYP17A1 (0.82) CYP19A1CYP17A1CYP3A4CYP11B1CYP11B2
SCHEMBL5821118 0.83 CYP19A1 (0.61) CYP19A1CYP17A1MEN1NR1I2USP2
SCHEMBL5821117 0.83 CYP19A1 (0.61) CYP19A1CYP17A1MEN1NR1I2USP2
SCHEMBL8535942 0.83 CYP19A1 (0.61) CYP19A1CYP17A1MEN1NR1I2USP2
SCHEMBL6977589 0.80 CYP17A1 (0.61) CYP19A1CYP17A1MEN1NR1I2USP2
SCHEMBL7276614 0.80 CYP17A1 (0.61) CYP19A1CYP17A1MEN1NR1I2USP2
SCHEMBL27565980 0.80 CYP17A1 (0.61) CYP19A1CYP17A1MEN1NR1I2USP2
SCHEMBL4578052 0.80 CYP17A1 (0.83) CYP19A1CYP17A1MEN1NR1I2USP2
SCHEMBL6983161 0.79 CYP24A1 (0.56) CYP19A1CYP17A1TDP1CYP24A1CYP27B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4339448-A Imidazole-copper complex compounds and fungicides containing them BASF AKTIENGESELLSCHAFT (DE) 1982-07-13 US claimed
US-4339448-A Imidazole-copper complex compounds and fungicides containing them BASF AKTIENGESELLSCHAFT (DE) 1982-07-13 US disclosed
US-4102891-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1978-07-25 US disclosed