Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971327 | 0.72 | KMT2A (0.36) | ALDH1A1KMT2A | |
| SCHEMBL6964143 | 0.72 | KMT2A (0.36) | ALDH1A1KMT2A | |
| SCHEMBL6964149 | 0.72 | KMT2A (0.36) | ALDH1A1KMT2A | |
| SCHEMBL6977597 | 0.70 | IDH1 (0.30) | — | |
| SCHEMBL247623 | 0.68 | MAPT (0.40) | KMT2AITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL6976606 | 0.67 | — | — | |
| SCHEMBL7180273 | 0.59 | CTRB1 (0.43) | ALDH1A1KDM4E | |
| SCHEMBL6999564 | 0.56 | SRC (0.44) | ALDH1A1KMT2AKDM4E | |
| SCHEMBL3069579 | 0.54 | — | — | |
| SCHEMBL12620555 | 0.54 | RIPK1 (0.56) | ALDH1A1KMT2AITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023265-B1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM CA LTD (CA) | 2003-01-15 | — | — | EP | disclosed |
| US-6211170-B1 | Azetidinone derivatives for the treatment of HCMV infections | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-04-03 | — | — | US | disclosed |