Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 4/20 | 0.36 |
| ▸ | DNMT3A | Q9Y6K1 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968017 | 0.88 | CCR8 (0.44) | CCR8KCNH2MTNR1AMTNR1BSLC6A4 | |
| SCHEMBL6971729 | 0.87 | CCR8 (0.52) | CCR8KCNH2MTNR1AMTNR1BSLC6A4 | |
| SCHEMBL6966012 | 0.86 | CCR8 (0.42) | CCR8KCNH2MTNR1AMTNR1BSLC6A4 | |
| SCHEMBL6969343 | 0.86 | CCR8 (0.42) | CCR8KCNH2MTNR1AMTNR1BCYP3A4 | |
| SCHEMBL6970280 | 0.86 | CCR8 (0.44) | CCR8KCNH2MTNR1AMTNR1BCYP3A4 | |
| SCHEMBL6972423 | 0.85 | CCR8 (0.43) | CCR8KCNH2CYP3A4 | |
| SCHEMBL6974682 | 0.85 | CCR8 (0.43) | CCR8KCNH2CYP3A4 | |
| SCHEMBL6965276 | 0.83 | CCR8 (0.53) | CCR8KCNH2MTNR1AMTNR1BSLC6A4 | |
| SCHEMBL6868975 | 0.82 | CCR8 (0.51) | CCR8KCNH2MTNR1AMTNR1BCYP3A4 | |
| SCHEMBL6965739 | 0.82 | DRD3 (0.45) | CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051413-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-04 | — | — | EP | claimed |