Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977896 | 1.00 | LMNA (0.66) | LMNASMN1; SMN2GFERNPSR1MCL1 | |
| SCHEMBL6977891 | 1.00 | LMNA (0.66) | LMNASMN1; SMN2GFERNPSR1MCL1 | |
| SCHEMBL6976254 | 0.92 | LMNA (0.56) | LMNASMN1; SMN2MCL1 | |
| SCHEMBL6982600 | 0.90 | LMNA (0.66) | LMNASMN1; SMN2GFERNPSR1P2RY1 | |
| SCHEMBL6981577 | 0.90 | LMNA (0.66) | LMNASMN1; SMN2GFERNPSR1P2RY1 | |
| SCHEMBL6981574 | 0.90 | LMNA (0.66) | LMNASMN1; SMN2GFERNPSR1P2RY1 | |
| SCHEMBL6982599 | 0.90 | LMNA (0.66) | LMNASMN1; SMN2GFERNPSR1P2RY1 | |
| SCHEMBL6981581 | 0.90 | LMNA (0.66) | LMNASMN1; SMN2GFERNPSR1P2RY1 | |
| SCHEMBL6976198 | 0.86 | MCL1 (0.55) | LMNASMN1; SMN2MCL1 | |
| SCHEMBL4129242 | 0.86 | LMNA (0.66) | LMNASMN1; SMN2GFERNPSR1P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216398-A1 | Soluble beta amyloid precursor protein secretion promoters | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2003-11-20 | — | — | US | disclosed |
| EP-1283055-A1 | SOLUBLE BETA AMYLOID PRECURSOR PROTEIN SECRETION PROMOTERS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216398-A1 | Soluble beta amyloid precursor protein secretion promoters | APP, BDNF, BACE1 | LMNA 1185/4885SMN1; SMN2 149/4885GFER 1016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.