Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 9/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | FABP4 | P15090 | 7/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29862413 | 0.88 | PLA2G2A (0.58) | PLA2G2AHTR6FABP4FABP3 | |
| SCHEMBL817701 | 0.88 | PLA2G2A (0.58) | PLA2G2AHTR6FABP4FABP3 | |
| Water SCHEMBL6981285 | 0.87 | PLA2G2A (0.57) | PLA2G2AHTR6FABP4FABP3 | |
| SCHEMBL818191 | 0.83 | PLA2G2A (0.53) | PLA2G2AHTR6 | |
| SCHEMBL29862380 | 0.83 | PLA2G2A (0.53) | PLA2G2AHTR6 | |
| SCHEMBL6699402 | 0.82 | HTR6 (0.71) | PLA2G2AHTR6 | |
| SCHEMBL29862561 | 0.80 | PLA2G2A (0.59) | PLA2G2AHTR6 | |
| SCHEMBL818539 | 0.80 | PLA2G2A (0.59) | PLA2G2AHTR6 | |
| SCHEMBL11838754 | 0.80 | HTR6 (0.56) | PLA2G2AHTR6FABP4 | |
| SCHEMBL6694891 | 0.79 | HTR6 (0.50) | PLA2G2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839806-B1 | Substituted tricyclics | LILLY CO ELI (US) | 2003-07-09 | — | — | EP | claimed |