Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 9/20 | 0.37 |
| ▸ | BRD4 | O60885 | 7/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968269 | 1.00 | CREBBP (0.37) | CREBBPBRD4EP300RAB9AALOX5 | |
| SCHEMBL6978352 | 0.67 | KMT2A (0.39) | — | |
| SCHEMBL12148832 | 0.66 | — | — | |
| SCHEMBL3818825 | 0.66 | CREBBP (0.45) | CREBBPBRD4EP300RAB9ADAO | |
| SCHEMBL6247618 | 0.64 | BRD4 (0.50) | CREBBPBRD4 | |
| SCHEMBL157619 | 0.64 | BRD4 (0.50) | CREBBPBRD4 | |
| SCHEMBL9295153 | 0.64 | BRD4 (0.50) | CREBBPBRD4 | |
| SCHEMBL8773531 | 0.63 | BRD4 (0.36) | CREBBPBRD4EP300ALOX5 | |
| SCHEMBL12064639 | 0.63 | SLC6A2 (0.45) | — | |
| SCHEMBL6540248 | 0.62 | DAO (0.36) | CREBBPALOX5DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023265-B1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM CA LTD (CA) | 2003-01-15 | — | — | EP | disclosed |
| US-6211170-B1 | Azetidinone derivatives for the treatment of HCMV infections | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-04-03 | — | — | US | disclosed |